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Cocaine blocks reuptake of adrenergics (ne/e), but i'm having trouble thicking about what that has to do with beta blockers, and how they even affect one another What does the nl in nl s1 s2 mean Furthermore, o2 binding to hb is subject to a phenomenon called cooperativity (1 o2 binding causes hb to bind the next o2 more strongly

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The first two bound o2 causes the 3rd o2 to bind even more strongly etc), hence the sigmoidal curve

Co does not display this phenomenon, therefore its curve is hyperbolic Take away, the hyperbolic shape can not become sigmoidal for any reason What is the difference in nomenclature between clearing and medically optimizing for surgery Is one favorable to other in terms of liability?

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